Rifapentine access in Europe: growing concerns over key tuberculosis treatment component

Incidence and factors associated with active tuberculosis among people living with HIV after long-term antiretroviral therapy in Thailand: a competing risk model

BACKGROUND: Antiretroviral therapy (ART) is known to reduce tuberculosis (TB) incidence among people living with HIV (PLWH). However, studies describing the impact of long-term ART and CD4 count recovery on TB incidence remain scarce due to limited …

Monocyte-to-lymphocyte ratio as a predictor of TB among people living with HIV

BACKGROUND: Diagnostic tools to identify incipient or subclinical TB stages will be helpful for preventive intervention. A simple biomarker to predict TB may be the monocytes to lymphocytes ratio (ML ratio) in peripheral blood.METHODS: We assessed …

Pathogen-free diagnosis of tuberculosis

Defining Outcomes of Tuberculosis (Treatment): From the Past to the Future.

Untreated active tuberculosis (TB) has a very high long-term mortality. Treatment of TB reduces mortality dramatically and should maximize cure, preventing ongoing transmission and TB sequelae. However, predicting the risk of failure and relapse is …

Use and impact of molecular methods for detecting drug-resistant TB.

The burden of tuberculosis; measuring uncertainty

How certain are published estimates on the burden of disease?

An easy tool to assess ventilation in health facilities as part of air-borne transmission prevention: a cross-sectional survey from Uganda

BACKGROUND: No guidelines exist on assessing ventilation through air changes per hour (ACH) using a vaneometer. The objective of the study was to evaluate the position and frequency for measuring air velocity using a vaneometer to assess ventilation …

Effect of secondary preventive therapy on recurrence of tuberculosis in HIV-infected individuals: a systematic review

Human immunodeficiency virus (HIV)-infected individuals successfully treated for tuberculosis (TB) remain at risk of recurrence of the disease, especially in high TB incidence settings. We performed a systematic review, investigating whether …

Tuberculosis Treatment Outcomes in Europe: Based on Treatment Completion, Not Cure