Humans

Clinical Reasoning Underlying Guideline Nonadherence in Urinary Tract Infections in Nursing Homes

Rifapentine access in Europe: growing concerns over key tuberculosis treatment component

Incidence and factors associated with active tuberculosis among people living with HIV after long-term antiretroviral therapy in Thailand: a competing risk model

BACKGROUND: Antiretroviral therapy (ART) is known to reduce tuberculosis (TB) incidence among people living with HIV (PLWH). However, studies describing the impact of long-term ART and CD4 count recovery on TB incidence remain scarce due to limited …

Monocyte-to-lymphocyte ratio as a predictor of TB among people living with HIV

BACKGROUND: Diagnostic tools to identify incipient or subclinical TB stages will be helpful for preventive intervention. A simple biomarker to predict TB may be the monocytes to lymphocytes ratio (ML ratio) in peripheral blood.METHODS: We assessed …

Pathogen-free diagnosis of tuberculosis

Diapers as Promising Alternative Collection Method for Urine Specimens in Nursing Home Residents: A Noninferiority Study.

OBJECTIVE: There is unmet need for an easy, noninvasive urine collection method to diagnose urinary tract infections (UTIs) in nursing home residents suffering from urinary incontinence or cognitive impairments. UTIs are highly prevalent in nursing …

Use and impact of molecular methods for detecting drug-resistant TB.

An easy tool to assess ventilation in health facilities as part of air-borne transmission prevention: a cross-sectional survey from Uganda

BACKGROUND: No guidelines exist on assessing ventilation through air changes per hour (ACH) using a vaneometer. The objective of the study was to evaluate the position and frequency for measuring air velocity using a vaneometer to assess ventilation …

Rapid assessment of antimicrobial resistance prevalence using a Lot Quality Assurance sampling approach

AIM: Increasing antimicrobial resistance (AMR) requires rapid surveillance tools, such as Lot Quality Assurance Sampling (LQAS). MATERIALS & METHODS: LQAS classifies AMR as high or low based on set parameters. We compared classifications with the …

Treatment Outcomes in Multidrug-Resistant Tuberculosis